![]() doi: 10.1001/jama.2021.16146Ĭorrection: This article was corrected on October 6, 2021, to correct an error in the Discussion that presented an incorrect positive predictive value for a SARS-CoV-2 test. Testing programs must consider what procedures have a high risk of transmission (eg, intubation and bronchoscopy aerosolize particles from the respiratory tract and are associated with higher transmission risk) and balance transmission risk reduction with potential harms to patients that result from delayed procedures following a positive test result.Ĭorresponding Author: KC Coffey, MD, MPH, University of Maryland School of Medicine, 10 S Pine St, MSTF 257-B, Baltimore, MD 21201 ( Online: September 17, 2021. The ability of preprocedural testing to prevent nosocomial COVID-19 transmission varies with disease prevalence, infection history, the patient’s immunization status, employee vaccination rate, and personal protective equipment availability. Estimating 99% sensitivity and 95% specificity for the presence of contagious SARS-CoV-2, the test positive predictive value was 6.5%. Thus, at the time of testing in this patient, the pretest probability of COVID-19 was approximately 0.35% (7-day cumulative average multiplied 5-fold to account for undertesting). Patients undergoing asymptomatic screening have a pretest probability of COVID-19 that mirrors local prevalence. There is no evidence of altered test performance with variants. 10 However, whether reinfection rates will increase due to Delta or other variants is unknown. 9 Reinfection with SARS-CoV-2 is rare (risk of reinfection, 0.17%). The Centers for Disease Control and Prevention recommend that patients infected within the past 90 days without new COVID-19 symptoms should not be retested. Because she remained asymptomatic, retesting provided no useful information. This patient had persistently positive RT-PCR test results for SARS-CoV-2 less than 90 days from prior infection. ![]() Shared Decision Making and Communication.Scientific Discovery and the Future of Medicine.Health Care Economics, Insurance, Payment.Clinical Implications of Basic Neuroscience. ![]()
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